何(なに)せat any rate, anyhow

住民(じゅうみん)：「大変(たいへん)だ、何(なに)せこの雪(ゆき)では出(で)かけられない。」

Resident: "This is terrible, at any rate, I can't go out in this snow." {at any rate, anyhow}

船長(せんちょう)：「困(こま)ったな〜。何(なに)せこの風(かぜ)では船(ふね)を出(だ)せないよ！」

Captain: "This is troublesome. At any rate, we can't set sail in this wind!" {at any rate, anyhow}

社員(しゃいん)：「今日(きょう)も残業(ざんぎょう)か。何(なに)せ、今日(きょう)中(じゅう)にこの仕事(しごと)を終(お)わらせないと。」

Employee: "Overtime again today, huh. At any rate, I have to finish this job by today." {at any rate, anyhow}

妻(つま)：「痩(や)せた？」夫(おっと)：「少(すこ)しね。何(なに)せ忙(いそが)しくてご飯(はん)を食(た)べる暇(ひま)さえないんだ。」

Wife: "Have you lost weight?" Husband: "A little, yes. At any rate, I've been so busy I haven't even had time to eat." {at any rate, anyhow}

彼女(かのじょ)に重(おも)い罰(ばつ)を与(あた)えることは出来(でき)ない。何(なに)せ、彼女(かのじょ)はまだほんの子供(こども)だから。

I can't impose a heavy punishment on her. At any rate, she is still just a child. {at any rate, anyhow}