詰(つ)まりthat is to say, that is, in other words, I mean, in short, in brief, to sum up, ultimately, in the end, in the long run, when all is said and done, what it all comes down to, when you get right down to it, basically, clogging, obstruction, stuffing, (degree of) blockage, shrinkage, end, conclusion, dead end, corner, distress, being at the end of one's rope

排水溝(はいすいこう)の詰(つ)まりを取(と)るために掃除(そうじ)をする。

Cleaning to remove blockage in a drainage ditch.

先生(せんせい)：「詰(つ)まり、あなたは留年(りゅうねん)ということです。」

Teacher: 'In other words, you’re going to repeat the year.'

地図(ちず)の上(うえ)の方(ほう)、詰(つ)まり北(きた)の方(ほう)は南(みなみ)の方(ほう)よりも寒(さむ)いです。

The upper part of the map—that is to say, the north—is colder than the south.

袖丈(そでたけ)の詰(つ)まり具合(ぐあい)が緩(ゆる)いので、このシャツは腕(うで)が太(ふと)い人(ひと)でも着(き)られます。

Since the tightness around the sleeves is loose, this shirt can even fit people with thick arms.

上司(じょうし)：「今(いま)まで色々(いろいろ)言(い)ってきたが、詰(つ)まり、私(わたし)が言(い)いたいのは皆(みな)が優秀(ゆうしゅう)だという事(こと)だ。」

Boss: 'I've said a lot up to now, but basically, what I'm trying to say is that everyone here is excellent.'