かくなる上(うえ)はnow that it's come to this, since it's come to this

東大(とうだい)に合格(ごうかく)した。かくなる上(うえ)はハーバードを目指(めざ)そう。

I got into the University of Tokyo. Since I've come this far, I’ll aim for Harvard.

かくなる上(うえ)は未婚(みこん)のまま猫(ねこ)と一緒(いっしょ)に生涯(しょうがい)を終(お)えるつもりだ。

Now that it's come to this, I intend to spend the rest of my life unmarried, with a cat.

家賃(やちん)が払(はら)えない。かくなる上(うえ)は路上(ろじょう)生活(せいかつ)をしようと考(かんが)えている。

I can't pay the rent. Now that it's come to this, I'm considering living on the streets.

妹(いもうと)が殺(ころ)されたので、かくなる上(うえ)は僕(ぼく)がリベンジをするつもりです。

My sister was murdered. Now that it's come to this, I'll get revenge myself.

バスが来(こ)ないが、バスしか移動(いどう)手段(しゅだん)がない。かくなる上(うえ)は待(ま)つしかない。

The bus isn't coming, but the it's the only means of transportation. Now that it's come to this, there's no choice but to wait.