尽(つ)きるto be used up, to be run out, to be exhausted, to be consumed, to come to an end

食料(しょくりょう)が尽(つ)きて餓死(がし)する。

Run out of food and starve to death. {to be used up, to be run out, to be exhausted, to be consumed, to come to an end}

万策(ばんさく)が尽(つ)きた。もう何(なに)も思(おも)いつきません。

I've exhausted all options. I can't think of anything else. {to be used up, to be run out, to be exhausted, to be consumed, to come to an end}

道(みち)が尽(つ)きたので、ここから先(さき)へは行(い)けません。

Since the road has ended, we cannot go any further from here. {to be used up, to be run out, to be exhausted, to be consumed, to come to an end}

生徒(せいと)が努力(どりょく)している限(かぎ)り、彼(かれ)らへの愛想(あいそ)が尽(つ)きることはありません。

As long as the students are making an effort, I will never run out of patience with them. {to be used up, to be run out, to be exhausted, to be consumed, to come to an end}

何(なん)度(ど)にも及(およ)ぶ失敗(しっぱい)経験(けいけん)は生(い)きる事(こと)への気力(きりょく)が尽(つ)きる原因(げんいん)となりかねません。

Repeated failures can potentially lead to a loss of will to live. {to be used up, to be run out, to be exhausted, to be consumed, to come to an end}