～てはIf, With, Since, Because

ては often marks a condition with a negative or cautionary result, as in 無駄遣いしては貯金できない (If you waste money, you can’t save). たって means even if or no matter, used casually like ても but with a rougher tone, as in 誰に聞いたって分からない (Even if you ask anyone, they won’t know).

ていては shows the continuation or repetition of an action and its negative consequences, often with a nuance of warning, as in 遊んでいては合格できない (If you keep playing, you won’t pass). ては marks a conditional result without the progressive sense, and can imply either positive or negative outcomes, as in 褒めてはやる気を出させた (By praising him, I motivated him).

ようでは・ようじゃ expresses concern or dissatisfaction, implying that if things stay as they are, the outcome will be undesirable, as in この成績では合格できないようじゃないか (With these grades, you won’t pass, will you?). ては introduces a condition leading to a result, which can be neutral or negative, as in 遊んでいては合格できない (If you keep playing, you won’t pass).