かくなる上(うえ)は

東大(とうだい)に合格(ごうかく)した。かくなる上(うえ)はハーバードを目指(めざ)そう。

I passed the University of Tokyo's entrance exam. Now that it's come to this, I should aim for Harvard. {now that it's come to this, since it's come to this}

かくなる上(うえ)は未婚(みこん)のまま猫(ねこ)と一緒(いっしょ)に生涯(しょうがい)を終(お)えるつもりだ。

Now that it's come to this, I intend to spend the rest of my life unmarried, with a cat. {now that it's come to this, since it's come to this}

家賃(やちん)が払(はら)えない。かくなる上(うえ)は路上(ろじょう)生活(せいかつ)をしようと考(かんが)えている。

I can't pay the rent. Now that it's come to this, I'm considering living on the streets. {now that it's come to this, since it's come to this}

妹(いもうと)が殺(ころ)されたので、かくなる上(うえ)は僕(ぼく)がリベンジをするつもりです。

Since my sister was killed, now that it's come to this, I intend to take revenge. {now that it's come to this, since it's come to this}

バスが来(こ)ないが、バスしか移動(いどう)手段(しゅだん)がない。かくなる上(うえ)は待(ま)つしかない。

The bus isn't coming, but the bus is the only means of transportation. Now that it's come to this, there's no choice but to wait. {now that it's come to this, since it's come to this}