打(う)ちのめすto knock down, to beat (someone) up, , to injure (someone) so badly they cannot recover (esp. emotionally), to overwhelm (with mental anguish, etc.)

う-verb (す), Transitive verb

1. 1.

   to knock (someone) down, to floor, to beat up

2. 2.

   to deal a devastating blow (from which one cannot recover), to devastate (emotionally), to crush, to overwhelm, to defeat resoundingly, to give (an opponent) a drubbing