のに Despite, Although, Even though

のに and ものの both express contrast, but differ in nuance and tone. のに is more casual and often conveys disappointment or regret. It can also end a sentence to imply 'If only (A)!'. ものの is more formal and means 'although (A), (B) didn't follow as expected,' often with an implicit contrast. Unlike のに, it is not generally used alone at the end of a sentence..

Both のに and くせに express contrast, but with different nuance. のに is relatively neutral, like 'although', while くせに adds a strong negative or critical tone. For example, 頭がいいのにやる気がない and 頭がいいくせにやる気がない both mean 'Although (he's) smart, (he) has no motivation.', the のに version is just stating a fact, while the くせに version implies that his lack of motivation is a negative trait and not befitting of him.

のに expresses contrast, similar to 'although,' and follows verbs, adjectives, or nouns (with な for nouns and な-adjectives). It's typically used at the end of a phrase or sentence. それなのに is a related form used at the beginning of a sentence, meaning 'and yet' or 'despite that,' with それ referring back to the previous statement.

のに expresses contrast, similar to 'although,' and follows verbs, adjectives, or nouns (with な for nouns and な-adjectives). It's typically used at the end of a clause or sentence. それでも also shows contrast, but appears at the beginning of a sentence. The それ refers to the previous statement, giving it the meaning of 'Even so' or 'But still.'

Both にしても and のに express contrast, but with different nuances. のに is a general contrastive expression, like 'although.' にしても often presents a hypothetical or assumed condition, followed by an unexpected result. Like other ～ても forms, it's commonly used with Wh-words, e.g. どこに行くにしても 'no matter where you go'.

Both のに and ながらも express contrast, but with different focuses. のに is more general and used widely, like the English 'although.' ながらも is mainly used with state-expressing verbs and conveys surprise that something happened despite that state.