なくちゃ・なきゃMust do, Have to do

なくちゃ (short forなくては), and なきゃ (short for なければ) are the most common colloquial abbreviations used to convey that something 'must', or 'has to' be done.

Like てはいけない (must not), なくてはいけない (must), and なくてはならない (must), these abbreviation forms can be followed by いけない, ならない, or だめ. However, they are usually omitted, without changing the meaning.

Structures like this are referred to as spoken/colloquial language. These casual variations can come across in a very similar way to words like 'gotta' in English.

In these examples, a variety of forms have been used naturally. There is no 'most natural' form, and it will often depend on the speaker as to which they choose.

As with almost all grammatical structures, the shortest variations (not including いけない, etc.) are the most casual/used the most often.

There are several other ways that these common abbreviations can appear based on region, or even an individual speaker's preference. An example of this is なけりゃ, which is a (very) casual form of なければ.

In this example, we can see that some of these less common variations are used specifically by certain genders (in general). なけりゃ itself tends to be used by male speakers, and may be considered a bit rougher than なきゃ, or なくちゃ, which can be used by anybody.